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Dab2 interacting protein

WebApr 1, 2002 · Dab2ip (DOC-2/DAB2 interacting protein) is a RasGAP protein which shows a growth-inhibitory effect in human prostate cancer cell lines. Recent studies have shown … WebSep 17, 2024 · Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein family, and functions as a …

DAB2IP Plays Important Clinical Significance and Correlates With …

WebDOC-2/DAB2 interacting protein (DAB2IP) is a RasGAP protein that shows a suppressive effect on cancer progression. Our previous study showed the involvement of transcription regulation of DAB2IP in metastasis of colorectal cancer (CRC). However, the molecular mechanisms of DAB2IP in regulating the progression of CRC need to be further explored. freezing kit for warts https://sunnydazerentals.com

miR-1307-3p promotes tumor growth and metastasis of …

WebOct 18, 2024 · Some GAPs can promote apoptosis of tumor cells to protect the organism. p120RasGAP, regulator of G-protein signaling 3 (RGS3), deleted in liver cancer 1 (DLC1), DOC-2/DAB2 interacting protein (DAB2IP), and STARD13 are typical examples because the five GAPs can influence the balance of antiapoptotic proteins and proapoptotic … Webdisabled homolog 2-interacting protein, ASK-interacting protein 1, DOC-2/DAB2 interactive protein, DOC2/DAB2 interactive protein GeneRIFs: Gene References Into Functions These findings suggest that Dab-2 is transiently upregulated and phosphorylated (particularly the p96 kDa isoform) in experimental autoimmune encephalomyelitis and … WebSep 26, 2024 · Orthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2024] Other designations. disabled homolog 2-interacting protein, ASK-interacting protein 1, ASK1-interacting protein 1, DAB2-interacting protein, DOC-2/DAB-2 interactive protein, disabled 2 interacting protein … fast and furious spy racers switch

DAB2IP modulates primary cilia formation associated with renal ...

Category:DAB2IP - Wikipedia

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Dab2 interacting protein

miR-1307-3p promotes tumor growth and metastasis of …

WebDab2IP, also known as apoptosis signal-regulating kinase-interacting protein-1 (ASK1), is a GTPase activating protein associated with aggressive metastatic prostate cancer , … WebDescription: Homo sapiens DAB2 interacting protein (DAB2IP), transcript variant 1, mRNA. (from RefSeq NM_032552) RefSeq Summary (NM_032552): DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 …

Dab2 interacting protein

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WebNov 18, 2016 · The cytoplasmic Ras-GAP protein DAB2IP (Disabled-2 Interacting Protein) is a negative modulator of multiple oncogenic pathways. DAB2IP is rarely mutated, but frequently downregulated or ... WebMay 18, 2010 · The N-terminal half of DAB2IP contains a protein kinase C (see 176960) conserved region-2 (C2) domain and a RasGAP domain. The C-terminal half contains a …

WebJul 15, 2016 · Overall, Dab2 acts as a scaffold protein by interacting with many, but not all, cargo receptors, and by establishing simultaneous contacts at the site of endocytosis, favoring recruitment of other adaptor proteins that are essential for endocytosis to occur. Disabled‐2, an obligatory intermediary in developmental processes WebJun 16, 2003 · Identification of Dvl-3 as a Dab2-interacting protein. (A) Schematic representation of the small-pool cDNA screening strategy using GST–PID.(B) Schematic representation of the domain structure of Dvl …

WebJan 1, 2024 · DAB2IP, DAB2 Interacting Protein; KIF3a, kinesin family member 3A; RCC, renal cell carcinoma; TCGA, The Cancer Genome Atlas. Discussion. Primary cilium is a microtubule-based structure that protrudes from the centrosomal mother centriole (also known as basal body) into the extracellular milieu [30]. Since cilium axoneme is … WebFeb 9, 2012 · This indicates that the interaction between Dab2 and a DPF-interacting protein is essential for Dab2 function when AP2 levels are low. This DPF-interacting …

WebMechanistically, DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP mRNA was down-regulated and inversely …

http://www.cancerindex.org/geneweb/DAB2.htm fast and furious spy racers tony and laylaWebMar 21, 2024 · DAB2IP (DAB2 Interacting Protein) is a Protein Coding gene. Diseases associated with DAB2IP include Medulloblastoma and Arteriosclerosis. Among its related … fast and furious ssjishmaelWeb丁香通为您提供DAB2RabbitpA商品详情介绍：价格：￥600 - 1800，货号：db9976，品牌：戴格，详见丁香通DAB2RabbitpA商品详情页； freezing lancashire cheeseWebOct 4, 2012 · Dab2ip (DOC-2/DAB2 interacting protein) is a member of the Ras GTPase-activating protein (GAP) family that has been previously shown to function as a tumor suppressor in several systems. Dab2ip is also highly expressed in the brain where it interacts with Dab1, a key mediator of the Reelin pathway that controls several aspects … freezing lamb chopsWebMar 21, 2024 · DAB2 (DAB Adaptor Protein 2) is a Protein Coding gene. Diseases associated with DAB2 include Teratocarcinoma and Hypercholesterolemia, Familial, 4 . … fast and furious spy racers voice actorsWebFeb 15, 2024 · Abstract. Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for multiple cellular functions. It is involved in many signaling pathways and plays an integral role in vesicular uptake and trafficking, modulating immune function, protein … fast and furious streamenWebFeb 3, 2015 · Dab2 is an adapter protein involved in receptor-mediated signaling, endocytosis, cell adhesion, hematopoietic cell differentiation, and angiogenesis. It plays … freezing latent heat