C. rodentium infection model
WebDec 30, 2013 · Citrobacter rodentium is an attaching and effacing pathogen used as a murine model for enteropathogenic Escherichia coli. The mucus layers are a complex matrix of molecules, and mucus swelling, hydration and permeability are affected by many factors, including ion composition. Here, we used the C. rodentium model to investigate mucus … WebJan 18, 2011 · The pathogenesis of a Citrobacter rodentium infection was evaluated in mice fed diets with a single deficiency in either selenium or vitamin E or with a double …
C. rodentium infection model
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WebJan 1, 2008 · There have been considerable advances in our understanding of the molecular pathogenesis of enteropathogenic Escherichia coli and enterohemorrhagic E. coli infection. Given the difficulty of infecting laboratory mice with these diarrhea-causing pathogens, a growing number of studies have found the murine bacterial pathogen … WebNov 1, 2024 · Citrobacter rodentium is a murine mucosal pathogen used as a model to elucidate the molecular and cellular pathogenesis of infection with two clinically …
WebNational Center for Biotechnology Information WebCitrobacter rodentium is a mucosal pathogen of mice that shares several pathogenic mechanisms with enteropathogenic Escherichia coli (EPEC) and …
WebJun 17, 2024 · Abstract:收起 Citrobacter rodentium is an extracellular enteric mouse-specific pathogen used to model infections with human pathogenic Escherichia coli and inflammatory bowel disease. C. rodentium injects type III secretion system effectors into intestinal epithelial cells (IECs) to target inflammatory, metabolic and cell survival … WebFeb 19, 2013 · The mouse pathogen C. rodentium is a widely used model for colonic infection and has been a major tool in fundamental discoveries in the fields of bacterial …
WebApr 5, 2024 · For Rodentibacter pneumotropicus, WSD fed mice with chronic infection with C. rodentium on day 35 post-infection were orally gavaged with 1 ×10 8 CFU/per mouse Rodentibacter pneumotropicus . C. rodentium fecal was monitored thereafter. For antibiotic treatment: GBC fed mice were infected with C. rodentium as described above. Some of …
WebJul 1, 2024 · Furthermore, recent reports indicate that C. rodentium and inflammatory bowel disease (IBD) induce similar T-cell responses (Higgins et al., 1999; Simmons et al., 2002), and the C. rodentium infection mouse model is a very useful tool to study intestinal colitis and pathology as well as the infection dynamics of attaching and effacing bacterial ... malian pronunciationWebDec 1, 2024 · Citrobacter rodentium is a key physiological model for studying A/E pathogenesis.. C. rodentium encodes effectors that subvert host cell death signaling.. C. rodentium modulates apoptosis to block neutrophil and Th17 cell recruitment.. RIPK3-dependent necroptosis limits C. rodentium persistence in host colon.. NLRP3 and … credit line increase citi cardWebFeb 1, 2024 · However, C. rodentium strains carrying virulence factors from human AE pathogens have been tested in mice [42 ••, 63], and such strategies, along with efforts to … credit line appWebC. rodentium is used as a model of human disease caused by pathogenic E. coli, so animals with active or prior infections will not be suitable for this research application. … credit karma legal complianceWebDec 17, 2008 · Background Bacterial gastroenteritis causes morbidity and mortality in humans worldwide. Murine Citrobacter rodentium infection is a model for gastroenteritis caused by the human pathogens … credit line rental vodafoneWebA dose of 10 µM avasimibe was sufficient to reduce S. enterica abundance in RAW264.7 macrophage-like cells. We conducted in vivo efficacy experiments using a mouse model in this study. Avasimibe intraperitoneal injection significantly reduced C. rodentium survival in mice, whether administered pre- or post-infection. malian pressWebSep 8, 2016 · Infection of mice with Citrobacter rodentium is a robust model to study bacterial pathogenesis, mucosal immunology, the health benefits of probiotics and the role of the microbiota during infection. Nature Protocols is an online journal publishing high-quality, citable, peer … malians pizza